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How do you define remission?
1INSERM, Hôpital de la Salpêtrière, Paris, France. lecru@ext.jussieu.fr
Objective:
To underscore the need to attain remission in the treatment of depression, taking into consideration the appropriate definitions of response and remission, as well as the impact of residual symptomatology.
Method:
A review of research pertaining to successful response and remission of depression following antidepressant intervention, as identified by a comprehensive MEDLINE search.
Results:
Complete remission is both critical and attainable with appropriate antidepressant therapy.
Conclusion:
While adequate response to antidepressant medication is desired, the ultimate goal of therapy is remission, the achievement of an asymptomatic state characterized by complete functional recovery.