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Radiculomyelitis complicating acute haemorrhagic conjunctivitis. A clinical study
Journal of the Neurological Sciences
|January 1, 1976
Summary
Acute haemorrhagic conjunctivitis (AHC) can lead to radiculomyelitis, causing leg weakness and paralysis. Public health control of AHC outbreaks is crucial to prevent disabling neurological complications.
Area of Science:
- Neurology
- Virology
- Public Health
Background:
- Acute haemorrhagic conjunctivitis (AHC) is a viral infection.
- Neurological complications following AHC are rare but can be severe.
Purpose of the Study:
- To investigate the clinical presentation and outcomes of radiculomyelitis following AHC.
- To identify the role of AHC virus in causing neurological disease.
Main Methods:
- Retrospective case series of 14 patients with radiculomyelitis post-AHC.
- Clinical examination, cerebrospinal fluid analysis, and electromyography were performed.
- Serological tests were conducted to confirm AHC virus infection.
Main Results:
- Patients developed limb weakness approximately 2 weeks after AHC onset.
- Common symptoms included fever, malaise, root pain, and flaccid paralysis.
- Cerebrospinal fluid showed lymphocytosis and elevated protein; EMG indicated motor neuron or root lesions.
- Virological studies confirmed AHC virus infection in 10 out of 12 patients.
- Corticosteroid treatment provided pain relief but did not significantly improve motor weakness.
- Motor function improved in 10 patients by 2 months, but 4 had persistent weakness.
Conclusions:
- Radiculomyelitis is a significant neurological complication of AHC.
- AHC virus is implicated in the pathogenesis of this neurological condition.
- Effective public health strategies are needed to control AHC outbreaks and prevent neurological sequelae.