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Updated: Sep 28, 2026

One-step Negative Chromatographic Purification of Helicobacter pylori Neutrophil-activating Protein Overexpressed in Escherichia coli in Batch Mode
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One-step Negative Chromatographic Purification of Helicobacter pylori Neutrophil-activating Protein Overexpressed in Escherichia coli in Batch Mode

Published on: June 18, 2016

[Relation between Helicobacter pylori and atopic diseases]

Gerardo López Pérez1, Fernando Alcántara Rodríguez

  • 1Servicio de Alergia, Instituto Nacional de Pediatria, Insurgentes Sur 2700-A, Col. Insurgentes Cuicuilco, CP 04530 México DF. api3@prodigy.net.mx

Revista Alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)
|December 28, 2002
PubMed

Insights

While infections may increase atopic diseases, the study found no direct link between Helicobacter pylori and allergies. Further research is needed to clarify its indirect role and potential treatment implications.

Area of Science:

  • Immunology
  • Microbiology
  • Allergology

Background:

  • Atopic diseases and infections are rising.
  • Infections can cause chronic inflammation and mast cell sensitization, leading to allergies.
  • Helicobacter pylori is a proposed bacterial agent linked to atopic diseases.

Purpose of the Study:

  • To review the scientific literature on the relationship between Helicobacter pylori infection and allergic diseases.
  • To determine if a direct causal link exists.
  • To explore potential indirect roles and future research directions.

Main Methods:

  • Bibliographical review of existing studies.
  • Analysis of evidence linking Helicobacter pylori to allergic conditions.
  • Assessment of the role of chronic inflammation and mast cell sensitization.

Main Results:

  • No direct causal evidence was found linking Helicobacter pylori infection to allergic diseases.
  • Helicobacter pylori may play an indirect role in the development or exacerbation of allergies.
  • The chronic inflammatory processes initiated by infections are key factors.

Conclusions:

  • Current evidence does not support a direct causal relationship between Helicobacter pylori and allergies.
  • Further controlled and randomized studies are essential to accurately define this relationship.
  • Helicobacter pylori eradication could be a potential therapeutic strategy for allergic patients, pending further evidence.

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