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[The role of substantia nigra in the cognitive activity in cats]
E I Mukhin1, Iu K Mukhina, T N Nabieva
1Brain Research Institute of the Russian Acad. Med. Sci., 105064, Moscow, 5, Per. Obukha, Russia.
Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova
|December 31, 2002
Abstract:
The role of substantia nigra (SN) in the cat cognitive activity of different complexity degree, was investigated by original technique. Neurosurgery or neurochemical SN switching off leads to reliable disturbances of condition, reflexes, generalization and abstraction. Rehabilitation was possible after pharmacological stimulation of dopaminergic, partly GABA-ergic, and cholinergic systems. Stimulation of serotonin system was ineffective.