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Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay
Published on: January 31, 2022
Acute iron ingestion
Tansu Sipahi1, Cemsit Karakurt, Arzu Bakirtas
1Dr. Sami Ulus Children's Hospital, Department of Pediatrics, Turkey. tansusipahi@hotmail.com
Insights
Acute iron poisoning in children requires prompt recognition and treatment. Early intervention, including whole bowel irrigation and deferoxamine, is critical for reducing severe outcomes from iron-containing product ingestion.
Area of Science:
- Pediatric Emergency Medicine
- Toxicology
- Clinical Case Reports
Background:
- Intoxication is a leading cause of pediatric emergency department admissions.
- The incidence of iron poisoning is rising due to the widespread availability of iron supplements.
Purpose of the Study:
- To report on five pediatric cases of acute iron ingestion.
- To highlight the importance of timely management in iron poisoning.
Main Methods:
- Case series of five pediatric patients admitted for iron ingestion.
- Treatment included gastric lavage, whole bowel irrigation for significant iron doses (>50 mg/kg), and deferoxamine when indicated.
Main Results:
- Management strategies were applied to pediatric patients with acute iron poisoning.
- The study involved five distinct cases requiring emergency intervention.
Conclusions:
- Prompt recognition and treatment are paramount in managing pediatric iron poisoning.
- Effective management can significantly decrease morbidity and mortality associated with iron-containing products.
Objective:
Intoxication is one of the most common causes of admissions to emergency department in pediatric age group. Incidence of iron poisoning gradually increased because of wide spread use of iron containing drugs.
Method:
In this report, we present five cases of iron ingestion who were admitted to our emergency department within a year.
Result:
Whole bowel irrigation in addition to gastric lavage with an iron dose of over 50 mg/kg as well as deferoxamine treatment for patients in whom clinical and laboratory indications are present.
Conclusion:
The prompt recognition and treatment of children with acute iron poisoning is the single and the most critical point for decreasing the morbidity and mortality associated with iron containing products.
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