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Updated: Aug 4, 2026
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Chromosome Preparation From Cultured Cells
Published on: January 28, 2014
Characterization of chromosomal aberrations in a case of glioblastoma multiforme combining cytogenetic and molecular
M A Zuber1, W Krupp, H Holland
1Institute of Human Genetics, University of, Leipzig, Germany. zubm@medizin.uni-leipig.de
Cancer Genetics and Cytogenetics
|December 31, 2002
Abstract:
A case of glioblastoma multiforme (GBM) that was investigated with a broad spectrum of cytogenetic and molecular cytogenetic techniques is reported. The results of cytogenetic studies, interphase fluorescence in situ hybridization, comparative genomic hybridization, and spectral karyotyping (SKY) are reported. Various structural chromosomal aberrations were identified, among which aberrations involving chromosome arm 2p were especially frequent. Using SKY, six translocations not previously described in GBM are reported.
