Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cortical frames of reference for eye-hand coordination.

Paul Van Donkelaar1, Ji-Hang Lee, Anthony S Drew

  • 1Department of Exercise and Movement Science, Institute of Neuroscience, University of Oregon, Eugene, OR 97403-1240, USA. paulvd@darkwing.uoregon.edu

Progress in Brain Research
|January 2, 2003
PubMed
Summary

The brain transforms visual information into arm movements using the posterior parietal cortex (PPC) and premotor cortex (PMC). Disrupting these areas partially impairs this visual-motor transformation.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

"It's more than just blood pressure and stitches": a critical examination of paramedic services from the perspectives of intimate partner violence advocates.

BMC health services research·2026
Same author

"I felt like I was providing half a service": Challenges, solutions, and action items for paramedicine when encountering patients experiencing intimate partner violence.

PloS one·2026
Same author

Large-scale modeling of axonal dynamic responses via deep learning.

Biomechanics and modeling in mechanobiology·2025
Same author

Reliability and Validity of the Modified Mini Cog: A Measure for Screening Cognitive Functions in Literates and Non-literates.

Journal of Nepal Health Research Council·2025
Same author

Publisher Correction: On-field Head Acceleration Exposure Measurement Using Instrumented Mouthguards: Missing Data Imputation for Complete Exposure Analysis.

Annals of biomedical engineering·2025
Same author

Intimate Partner Violence and Paramedicine: An Updated Scoping Review of Perspectives and Practices.

Prehospital emergency care·2025

Area of Science:

  • Neuroscience
  • Motor Control
  • Cognitive Neuroscience

Background:

  • The brain integrates visual input with motor commands for goal-directed actions like reaching.
  • Neural networks, including the posterior parietal cortex (PPC) and premotor cortex (PMC), are crucial for this visual-to-motor transformation.
  • Understanding the precise roles of PPC and PMC in sensorimotor control is an ongoing area of research.

Purpose of the Study:

  • To investigate the functional contribution of the PPC and PMC to the visual-to-motor transformation during reaching.
  • To examine how dissociating eye and limb movement amplitudes affects this neural transformation.
  • To assess the impact of disrupting PPC or PMC activity on the successful execution of the transformation.

Main Methods:

  • Review of neurophysiological experiments examining neural activity during reaching tasks.

Related Experiment Videos

  • Analysis of behavioral data under conditions where eye and limb movement amplitudes were dissociated.
  • Application of transcranial magnetic stimulation (TMS) to transiently disrupt PPC and PMC function.

    • Main Results:

    • The PPC-PMC network partially fails to complete the visual-to-motor transformation when eye and limb movement amplitudes are dissociated.
    • Disruption of PPC or PMC using TMS significantly impairs the ability to successfully perform the visual-to-motor transformation.
    • Evidence suggests these areas are critical but not solely sufficient for accurate sensorimotor mapping.

    Conclusions:

    • The PPC and PMC play essential, yet interdependent, roles in the brain's visual-to-motor transformation for reaching.
    • The ability of this network to accurately map visual information to motor output is sensitive to the relationship between eye and limb movement parameters.
    • Targeted disruption of PPC or PMC highlights their necessity for successful sensorimotor control.