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[Microneurosurgical treatment for gliomas located in lateral fissure area]
Yong-gao Mu1, Xiang-heng Zhang, Li-xiong Pan
1Department of Neurosurgery, Cancer Center, Sun Yat-sen University, Guangzhou 510060, P. R. China.
Background & Objective:
It has been generally recognized that extensive resection for gliomas is directly associated with better prognosis of the patients. However, some tumors in functional area are not easy to be radically resected and neurological deficiency could be resulted by surgery. This study was designed to investigate whether gliomas located in lateral fissure area could be radically resected without neurological deficiency.
Methods:
There were 22 gliomas located in lateral fissure area underwent microsurgical resection. The main branches of middle cerebral artery were preserved and the patients, if any neurological disfunction occurrence, were treated accordingly.
Results:
All 22 gliomas were totally or subtotally resected using microneurosurgical technique. In 7 cases the reserved functional vessels which pass through tumor mass, look like "bridge" after tumor resection. Six patients resulted in motor disfunction following surgery, in which 5 cases were recovered and KPS reached 70 after 6 months.
Conclusion:
Gliomas located in lateral fissure area could be radically resected under microscope resulting no neurological deficiency, if any, will recover.
Insights
Radical resection of gliomas in the lateral fissure area is achievable with microneurosurgery, preserving neurological function. Post-operative deficits are rare and often temporary, improving patient prognosis.
Area of Science:
- Neurosurgery
- Oncology
- Neuroscience
Context:
- Glioma resection in functional areas poses challenges due to potential neurological deficits.
- The lateral fissure area presents unique surgical difficulties for complete tumor removal.
- Maximizing tumor resection is crucial for improving glioma patient outcomes.
Purpose:
- To evaluate the feasibility and safety of radical resection for gliomas in the lateral fissure area.
- To assess the incidence of neurological deficits following microsurgical resection of these tumors.
- To determine the functional recovery rates in patients undergoing such procedures.
Summary:
- Microsurgical resection was performed on 22 gliomas in the lateral fissure area.
- Total or subtotal resection was achieved in all cases, preserving critical middle cerebral artery branches.
- While 6 patients experienced temporary motor dysfunction, 5 recovered significantly within 6 months.
Impact:
- Demonstrates that gliomas in the lateral fissure area can be radically resected with acceptable neurological outcomes.
- Highlights the efficacy of microneurosurgical techniques in managing challenging brain tumors.
- Suggests that aggressive surgical management can lead to improved prognosis without permanent functional impairment.
