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Potassium superoxide as an alternative reagent for Winterfeldt oxidation of beta-carbolines
Weiqin Jiang1, Xuqing Zhang, Zhihua Sui
1Johnson & Johnson Pharmaceutical Research & Development, L.L.C., 1000 Route 202 South, P.O. Box 300, Raritan, NJ 08869, USA. Wjiang1@prdus.jnj.com
Abstract:
Potassium superoxide was examined as an alternative oxidation reagent for the Winterfeldt reaction. KO(2) was found to be superior to the original Winterfeldt protocol for base-sensitive substrates. [reaction--see text]
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