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Updated: Jul 27, 2026

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability
Published on: August 6, 2021
Retinal vein occlusion in lymphomatoid papulosis
K Ramaesh1, H Monaghan, D Kemmett
1Princess Alexandra Eye Pavilion, Edinburgh, UK.
Purpose:
To describe an unusual patient who presented with hemi-retinal vein occlusion and lymphomatoid papulosis (LyP).
Methods:
Clinicopathological case study.
Results:
A 42 year old female patient presented with blurring of vision in her left eye and a nodular eruption of the skin involving arms, face and torso. She also complained of a non-itchy, blotchy rash on the arms, face and torso lasting for period of three months. Ocular examination showed a left superior hemi-retinal vein occlusion. The nodules resolved spontaneously over a period of two-three weeks leaving a faint scar. Hematological and systemic evaluation for auto-immune disorders, hypercoagulability, systemic malignancy and lymphoma were negative. A biopsy of the skin nodule was performed which showed infiltration of lymphoid blast cells which were CD30 positive. Based on the clinicopathological features a diagnosis of lymphomatoid papulosis (LyP) was made.
Conclusions:
Clinical and pathological features of this patient may suggest the retinal vein occlusion may be secondary to LyP.

