Using chronic pain to predict depressive morbidity in the general population

¹Stanford Sleep Epidemiology Research Center, School of Medicine, Stanford University, 3430 W Bayshore Rd, Suite 102, Palo Alto, CA 94303, USA. mohayon@stanford.edu

|January 7, 2003

Summary

Chronic painful physical conditions (CPPCs) are significantly linked to major depressive disorder. Individuals with CPPCs are four times more likely to have depression, highlighting the need for integrated care.

Area of Science:

Psychiatry
Epidemiology
Public Health

Background:

Pain and depression are frequently comorbid conditions.
Chronic painful physical conditions (CPPCs) may influence the development or exacerbation of depression.

Purpose of the Study:

To determine the prevalence of CPPCs in a large, multi-country European population.
To investigate the association between CPPCs and major depressive disorder.

Main Methods:

A cross-sectional telephone survey was conducted with 18,980 participants aged 15-100 years across the UK, Germany, Italy, Portugal, and Spain.
The Sleep-EVAL system was used to gather data on mental disorders and medical conditions, including specific questions about pain and a list of 42 diseases.
Prevalence and associations were analyzed using statistical methods, including logistic regression.

Main Results:

17.1% of participants reported at least one CPPC.
Major depressive disorder was diagnosed in 4.0% of subjects, with 43.4% of these individuals having at least one CPPC.
CPPCs were strongly associated with major depressive disorder (odds ratio = 4.0), and the presence of pain independently contributed to the diagnosis.

Conclusions:

The study confirms a significant association between chronic painful physical conditions and major depressive disorder.
The findings suggest that patients presenting with CPPCs should be routinely screened for depression.
Addressing chronic pain may be crucial in managing and preventing depression.

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Using chronic pain to predict depressive morbidity in the general population

Area of Science:

Background:

Purpose of the Study:

Main Methods:

Main Results:

Conclusions:

Related Concept Videos

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