Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

DicodonUse: the programme for dicodon bias visualization in prokaryotes.

J Paces1, V Paces

  • 1Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague, Czech Republic. paces@img.cas.cz

Folia Biologica
|January 7, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

COVID-19 and the immune system.

Physiological research·2020
Same author

Effect of stereospecific hydroxylation of N(6)-(Δ (2)-Isopentenyl)adenosine on cytokinin activity.

Planta·2013
Same author

The Rhodobacter capsulatus genome.

Photosynthesis research·2005
Same author

Improved synthesis, antibacterial activity and potential carcinogenicity of 5-amino-1 ,2,4-thiadiazol-3(2H)-one.

Die Pharmazie·2004
Same author

Cloning and expression of PARP-3 (Adprt3) and U3-55k, two genes closely linked on mouse chromosome 9.

Folia biologica·2002
Same author

Genetic determination of polyhydroxyalkanoate metabolism in Rhodobacter capsulatus SB1003.

Folia biologica·2002
Same journal

MiR-335-3p Alleviates Adipogenesis and Inflammation in Bone Marrow-Derived Mesenchymal Stem Cells in Osteoporotic Fractures.

Folia biologica·2026
Same journal

Research on the Diagnostic Potential of miR-383-5p in Rheumatoid Arthritis.

Folia biologica·2026
Same journal

The Predictive Value of NLRP3-Mediated Inflammatory Factor Production for Abnormal Liver Function in Pregnant Women with Hepatitis B.

Folia biologica·2026
Same journal

Mechanism Study and Analysis of Correlation between miR-409-3p and Post-Stroke Cognitive Impairment.

Folia biologica·2026
Same journal

Correlation between circ_0092576 and Arterial Stenosis Severity and Inflammatory Status in Patients with Coronary Heart Disease and Its Clinical Value.

Folia biologica·2026
Same journal

Intravitreal Application of Mesenchymal Stem Cell By-Products Does Not Ameliorate Experimental Autoimmune Uveitis.

Folia biologica·2026
See all related articles

The DicodonUse program quickly assesses prokaryotic gene content using dicodon frequencies. It differentiates genuine genes from non-coding sequences and distinguishes native genes from horizontally acquired ones.

Area of Science:

  • Bioinformatics
  • Genomics
  • Computational Biology

Background:

  • Prokaryotic genome analysis requires accurate gene identification.
  • Distinguishing intrinsic genes from horizontally acquired genes is crucial for understanding genome evolution.
  • Existing methods for gene assessment can be time-consuming.

Purpose of the Study:

  • To develop a rapid and straightforward method for assessing gene content in prokaryotic nucleotide sequences.
  • To differentiate true genes from open reading frames (ORFs) that are not genes.
  • To distinguish between genes native to a genome and those acquired through horizontal gene transfer.

Main Methods:

  • Utilizing the DicodonUse program for sequence analysis.
  • Analyzing frequencies of dicodons (pairs of adjacent codons) specific to an organism.

Related Experiment Videos

  • Applying dicodon frequency profiles to identify gene structures and origins.

    • Main Results:

    • The DicodonUse program effectively identifies open reading frames.
    • It successfully distinguishes between genuine genes and non-gene ORFs.
    • The program accurately differentiates between intrinsic and acquired genes within prokaryotic genomes.

    Conclusions:

    • Dicodon frequency analysis provides a fast and simple method for prokaryotic gene assessment.
    • This approach aids in understanding genome composition and evolutionary history.
    • DicodonUse offers a valuable tool for genomic research.