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Nitric oxide in liver transplantation: pathobiology and clinical implications
1GI Research Unit and Advanced Liver Disease Study Group, Department of Medicine, Alfred 2-435, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. shah.vijay@mayo.edu.
Abstract:
The gaseous molecule nitric oxide is involved in a variety of liver transplant-relevant processes, including ischemia-reperfusion injury, acute cellular rejection, and circulatory changes characteristic of advanced liver disease. This review article focuses on new advances relating to the role of nitric oxide in these syndromes with an emphasis on pathobiology and potential clinical implications.