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Spontaneous rat bite fever in non-human primates: a review of two cases
C R Valverde1, L J Lowenstine, C E Young
1Department of Surgery and Radiology Sciences, School of Veterinary Medicine, University of California, Davis, CA 95616, USA. crvalverde@ucdavis.edu
Abstract:
Rat bite fever is a worldwide zoonotic, non-reportable disease. This entity encompasses similar, yet distinct, disease syndromes caused by Streptobacillus moniliformis or Spirillum minus. Naturally occurring rat bite fever has not been previously described in non-human primates. This report describes two cases of non-human primate rat bite fever caused by S. moniliformis; a rhesus macaque (Macaca mullata) with valvular endocarditis, and a titi monkey (Callicebus sp.) with septic arthritis. Potential sources of infection included direct contact, and ingestion of surface water or feed contaminated with rodent feces.
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