Related Experiment Video
Updated: Jul 26, 2026

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
Published on: January 16, 2019
ALFRED: the ALelle FREquency Database. Update
H Rajeevan1, M V Osier, K-H Cheung
1Department of Genetics, Yale University School of Medicine, New Haven, CT 06520-8005, USA.
Abstract:
Elaboration of ALFRED (http://alfred.med.yale.edu) is being continued in two directions. One of which is developing tools for efficiently annotating the entries and checking the integrity of the data already in the database while the other is to increase the quantity and accessibility of data. Information contained in ALFRED such as, polymorphic sites, number of populations and frequency tables (one sample typed for one site) has significantly increased.
Related Concept Videos
Multiple Allele Traits
Frequency-dependent Selection
What is Population Genetics?
Hardy-Weinberg Principle
Mutation, Gene Flow, and Genetic Drift
Multiple Allele Traits

