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Percutaneous management of occlusive arterial disease associated with vasculitis: a single center experience

M Both1, T Jahnke, E Reinhold-Keller

  • 1Department of Radiology, Christian-Albrechts-University of Kiel, Kiel, Germany. mboth@rad.uni-kiel.de

Cardiovascular and Interventional Radiology
|January 15, 2003
PubMed

Insights

Percutaneous transluminal angioplasty shows promising safety and effectiveness for treating arterial disease in patients with vasculitis. This interventional therapy achieved high technical success rates with a low complication rate.

Area of Science:

  • Interventional Cardiology
  • Vascular Medicine
  • Rheumatology

Background:

  • Systemic vasculitis can lead to significant occlusive arterial disease.
  • Large vessel vasculitis, including giant cell arteritis and Takayasu arteritis, poses challenges for treatment.
  • Interventional radiology offers potential solutions for managing these vascular complications.

Purpose of the Study:

  • To assess the safety and effectiveness of percutaneous transluminal angioplasty (PTA) in patients with vasculitis-associated occlusive arterial disease.
  • To evaluate the outcomes of PTA and stent placement in treating various arterial lesions.
  • To determine the complication rates and long-term success of interventional therapy in this patient population.

Main Methods:

  • Eleven patients with diagnosed large vessel vasculitis underwent interventional treatment.
  • Thirty-three occlusive arterial lesions were treated using balloon angioplasty and/or stent placement.
  • Follow-up involved clinical assessments, angiography, and color duplex ultrasound.

Main Results:

  • 100% technical success for stenoses and 50% for occlusive lesions.
  • Complications included dissection (3 patients) and arterial rupture with hematoma (1 patient).
  • Restenosis occurred in 8 areas, with 4 lesions requiring repeat PTA; cumulative success rates ranged from 67.6% to 75.9%.

Conclusions:

  • Interventional therapy, including angioplasty, demonstrates promising technical success and follow-up results for vasculitis-related arterial disease.
  • While arterial injury is possible, the complication rate associated with PTA is generally low.
  • PTA is a viable option for managing occlusive arterial disease in patients with systemic vasculitis.

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