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In search of lipid translocases and their biological functions
Dick Hoekstra1, Sven C D van IJzendoorn
1Department of Membrane Cell Biology, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands.
Developmental Cell
|January 18, 2003
Abstract:
In plasma membranes, lipids distribute asymmetrically across the bilayer, a process that requires proteins. Recent work identified novel lipid translocators in yeast, and their activity was functionally correlated to endocytosis, thus boosting investigations on identity, mechanism, and function of lipid translocases.