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[Orofacial clefts in western Slovakia].

E Machácová1, R Bánsky, M Spaleková

  • 1Ustav epidemiológie, LF UK Bratislava.

Epidemiologie, Mikrobiologie, Imunologie : Casopis Spolecnosti Pro Epidemiologii a Mikrobiologii Ceske Lekarske Spolecnosti J.E. Purkyne
|January 21, 2003
PubMed
Summary
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Orofacial clefts, common birth defects, occurred at a rate of 1.61 per 1000 live births in western Slovakia. Incidence was higher in Bratislava and males, with palate clefts most frequent.

Area of Science:

  • Medical Science
  • Public Health
  • Pediatrics

Context:

  • Orofacial clefts represent a significant group of congenital anomalies.
  • Understanding their epidemiological patterns is crucial for public health initiatives.

Purpose:

  • To determine the incidence and epidemiological characteristics of orofacial clefts in western Slovakia.
  • To analyze variations in incidence across different regions and demographic groups.

Summary:

  • The study analyzed 629 cases of orofacial clefts among 390,404 live births in western Slovakia (1985-1999).
  • The overall incidence was 1.61 per 1000 live births, with higher rates in Bratislava compared to the wider region.
  • Incidence varied between districts (1.20-2.04/1000), was higher in males, and most commonly affected the primary and secondary palate.

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Impact:

  • Provides essential epidemiological data on orofacial clefts in a specific European population.
  • Highlights regional and demographic disparities that may inform targeted prevention and intervention strategies.
  • Identifies a discrepancy in recorded versus notified cases, suggesting potential improvements in data collection systems.