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An Ex Vivo Tissue Culture Model of Cartilage Remodeling in Bovine Knee Explants
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Published on: November 3, 2019

Effects of growth factors on the quality of ex vivo-generated cartilage

R James Koch1

  • 1Facial Plastic & Reconstructive Surgery, Division of Otolaryngology-Head and Neck Surgery, Stanford University Medical Center, Stanford, CA 94305-5328, USA. rjk@stanford.edu

Archives of Facial Plastic Surgery
|January 21, 2003
PubMed
Abstract

No abstract available in PubMed .

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Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...