Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Fast, economical technique for separating serum from blood samples.

G S Ahluwalia, Z J Kuczala, L R Carlson

    Clinical Chemistry
    |April 1, 1976
    PubMed
    Summary

    Polystyrene beads effectively separate serum from blood, showing no significant differences in 23 serum constituents compared to conventional methods. This bead-based method offers a viable alternative for blood sample processing.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    HL-91-technetium-99m: a new marker of viability in ischemic myocardium.

    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology·1999
    Same author

    Decay rates of anti-HIV dideoxynucleotides in tissue culture systems: a simple correction for the effect of cell replication.

    Drug metabolism and disposition: the biological fate of chemicals·1997
    Same author

    2',3'-Didehydro-3'-deoxythymidine: regulation of its metabolic activation by modulators of thymidine-5'-triphosphate biosynthesis.

    Molecular pharmacology·1996
    Same author

    Studies on the mechanism of action of 1-beta-D-arabinofuranosyl-5-azacytosine (fazarabine) in mammalian lymphoblasts.

    Journal of experimental therapeutics & oncology·1996
    Same author

    Comparison of the DNA incorporation in human MOLT-4 cells of two 2'-beta-fluoronucleosides, 2'-beta-fluoro-2',3'-dideoxyadenosine and fialuridine.

    Journal of pharmaceutical sciences·1996
    Same author

    Enhancement by 2'-deoxycoformycin of the 5'-phosphorylation and anti-human immunodeficiency virus activity of 2',3'-dideoxyadenosine and 2'-beta-fluoro-2',3'-dideoxyadenosine.

    Molecular pharmacology·1994

    Area of Science:

    • Biochemistry
    • Clinical Chemistry
    • Hematology

    Background:

    • Accurate serum separation is crucial for reliable diagnostic testing.
    • Conventional methods can be time-consuming and may affect analyte stability.

    Purpose of the Study:

    • To assess the efficacy of polystyrene beads in serum separation from whole blood.
    • To compare the accuracy of serum constituents obtained using polystyrene beads versus conventional methods.

    Main Methods:

    • Paired blood samples were utilized for analysis.
    • Serum was separated using polystyrene beads and a single centrifugation step.
    • Serum constituents were analyzed, and results were compared to a conventional separation method.

    Main Results:

    • Analysis of 23 different serum constituents showed no statistically significant differences between the two methods.
    • Statistical evaluation using z-test and regression analysis confirmed the equivalence of the methods.

    Conclusions:

    • Polystyrene beads provide an effective and comparable alternative for serum separation.
    • The bead-based method simplifies blood processing without compromising the integrity of key serum analytes.

    Related Experiment Videos