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[Study of peak expiratory flow in 728 normal adolescents in Chengdu area]
1Department of Physiology, School of Basic Medical Sciences, WCUMS, Chengdu 610041, China.
Objective:
This study was carried out to build the normal values and regression equations of peak expiratory flow (PEF) in normal adolescents.
Methods:
PEF and routine ventilatory functions, FVC, V75, V50, V25 were measured in 728 normal adolescents aged 8-19.
Results:
The PEF and FVC, V75, V50, V25 rose with the increase of age. The regression equations showed that PEF was highly positively correlated with age and FVC both in male and female adolescents, and also positively correlated with body weight in males; the coefficients of multiple correlation were 0.85 and 0.78 in male and female ones respectively. Correlations of PEF with V75, V50, V25 were also high, especially with V75 of which the correlation coefficients came up to 0.98 both in male and female adolescents. The coefficients of variation were 15%-20% both in male and female adolescents, and were in normal ranges.
Conclusion:
The normal ranges and regression equations of PEF provided for normal adolescents can be used to evaluate the pulmonary functions of patients who are in the same age-group suffering from bronchial asthma and other respiratory diseases.