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[A comparative study of serum sFas in patients with hepatocellular cancer and chronic hepatitis]
1Department of Infectious Disease, Second Xiangya Hospital, Central South University, Chiangsha 410011, China.
Objective:
To study the effects of sFas in hepatocellular cancer (HCC) and chronic hepatitis (CH).
Methods:
The serum sFas was detected in 18 patients with HCC, 12 patients with CH and 6 cases of normal control by ELISA.
Results:
The serum sFas in HCC was obviously increased and had significant difference with the patients of CH and normal control (P < 0.01). The serum sFas had positive correlation with the serum TBIL(P < 0.01), but negative correlation with the ALB, PTA and the ratio of ALT/AST(P < 0.01).
Conclusions:
sFas may resist the occurrence of HCC apoptosis. In CH, sFas has correlation with the severity of CH. The role of sFas in viral hepatitis is uncertain.
