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Updated: Sep 27, 2026

Human Liver Spheroids from Peripheral Blood for Liver Disease Studies
Published on: January 27, 2023
[Simultaneously analysis of 15 parameters in the patients with the liver-blood deficiency syndrome]
1Institute of Combined Traditional Chinese and Western Medicines, Xiangya Hospital, Central South University, Changsha 410008, China.
Objective:
Using HPLC-ED or RIA, we determined simultaneously 15 indexes in 27 patients with the liver-blood deficiency syndrome (LDBD). By means of multivarivate hierarchical cluster analysis and selections of typical variate, the results showed that 15 indexes were classified into 5 groups, and the typical variates of each groups were NE, T3, TXB2, ALD and cGMP. It suggests that LBDS has some pathopysiological characteristics such as decreased functions of sympathetic nerve activation, lower T3 syndrome, imbalance of the active substance regulating cardiovascular function and metabolism of salt and water, and abnormalities second signal substance in cellular membrane.
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