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MRI of the liver: can True FISP replace HASTE?
Christoph U Herborn1, Florian Vogt, Thomas C Lauenstein
1Department of Diagnostic and Interventional Radiology, University Hospital Essen, Hufelandstrasse 55, D-45122 Essen, Germany. christoph.herborn@uni-essen.de
Purpose:
To determine the diagnostic accuracy of two fast breath-hold magnetic resonance (MR) imaging sequences, half-Fourier acquired single turbo spin-echo (HASTE) and true fast imaging with steady state precession (TrueFISP), for the detection and characterization of focal liver lesions
Materials And Methods:
A total of 186 patients with suspected focal liver lesions were enrolled in this study. All patients underwent the same standardized study protocol including HASTE and TrueFISP. A consensus reading based on all available image data served as a standard of reference for classifying lesions into cysts, hemangiomas, focal nodular hyperplasia, or malignant/other lesions. All malignant lesions, as well as hepatic adenomas and abscesses, were histologically verified. Each separated by an eight-week interval, HASTE and TrueFISP images were retrospectively reviewed in random order for the detection and characterization of focal hepatic lesions. Finally, a receiver operating characteristic (ROC) analysis was calculated.
Results:
HASTE images had an overall sensitivity of 0.86 and a specificity of 0.91, whereas TrueFISP showed an overall sensitivity and specificity of 0.79 and 0.83, respectively (p>0.1).
Conclusion:
Neither HASTE nor TrueFISP alone are sufficient for the detection and characterization of hepatic lesions.
Insights
Neither half-Fourier acquired single turbo spin-echo (HASTE) nor true fast imaging with steady state precession (TrueFISP) MRI sequences alone are sufficient for diagnosing liver lesions. Further investigation is needed for accurate detection and characterization.
Area of Science:
- Radiology
- Medical Imaging
- Hepatology
Background:
- Focal liver lesions require accurate detection and characterization for appropriate patient management.
- Fast breath-hold magnetic resonance (MR) imaging sequences offer potential for improved liver lesion assessment.
Purpose of the Study:
- To evaluate the diagnostic accuracy of HASTE and TrueFISP MR imaging sequences for detecting and characterizing focal liver lesions.
- To compare the performance of HASTE and TrueFISP in liver lesion diagnosis.
Main Methods:
- 186 patients with suspected focal liver lesions underwent MR imaging using both HASTE and TrueFISP sequences.
- Lesion classification was based on a consensus reading, with malignant lesions and certain benign types histologically verified.
- Receiver operating characteristic (ROC) analysis was performed to assess diagnostic performance.
Main Results:
- HASTE sequences demonstrated a sensitivity of 0.86 and specificity of 0.91.
- TrueFISP sequences showed a sensitivity of 0.79 and specificity of 0.83.
- The differences in diagnostic accuracy between HASTE and TrueFISP were not statistically significant (p>0.1).
Conclusions:
- Neither HASTE nor TrueFISP imaging sequences, when used alone, are adequate for the definitive detection and characterization of focal liver lesions.
- Combined or additional imaging techniques may be necessary for comprehensive liver lesion assessment.