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[Development of integrated capillary electrophoresis chips]
Se Pu = Chinese Journal of Chromatography
|January 25, 2003
Summary
Integrated capillary electrophoresis (CE) chips offer high separation efficiency and sensitivity in microdevices. This review covers the development and applications of these advanced microfluidic analytical systems.
Area of Science:
- Analytical Chemistry
- Microfluidics
- Separation Science
Context:
- Capillary electrophoresis (CE) is a powerful separation technique.
- Microfabrication enables the miniaturization of analytical devices.
- Integrated capillary electrophoresis (ICE) chips combine CE with microfluidic technology.
Purpose:
- To systematically review the development of integrated capillary electrophoresis chips.
- To highlight the diverse applications of ICE chips.
- To provide an overview of recent advancements in microchip CE.
Summary:
- Microfabrication allows complex channel networks and functional units on a single chip.
- ICE chips provide high separation efficiency, good sensitivity, low reagent consumption, and short analysis times.
- The review covers developments and applications of ICE chips over the last decade, citing 39 references.
Impact:
- Demonstrates the suitability of CE for integration into planar microdevices.
- Facilitates the development of portable and automated analytical systems.
- Highlights the potential of microchip CE for various analytical challenges.