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[Solid-phase microextraction for the analysis of drugs and biological samples]
1Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China.
Se Pu = Chinese Journal of Chromatography
|January 25, 2003
Summary
Solid-phase microextraction (SPME) is a modern sample preparation method. This review covers its applications in analyzing drugs and biological samples, categorizing 60 references by analysis type.
Area of Science:
- Analytical Chemistry
- Biochemistry
- Forensic Science
Context:
- Solid-phase microextraction (SPME) emerged in the 1990s as a novel sample pretreatment technique.
- Its adoption has grown significantly in the analysis of complex matrices.
- SPME offers advantages in reduced solvent consumption and simplified procedures.
Purpose:
- To review the diverse applications of SPME in the analysis of drugs.
- To consolidate the use of SPME in the examination of biological samples.
- To systematically classify existing literature on SPME applications based on analytical characteristics.
Summary:
- This review examines the application landscape of SPME for drug and biological sample analysis.
- It synthesizes findings from 60 references, highlighting the technique's versatility.
- References are categorized into twelve groups based on the specific analytical objectives and methods employed.
Impact:
- Provides a comprehensive overview of SPME utility in pharmaceutical and biomedical fields.
- Facilitates researchers in selecting appropriate SPME methodologies for specific analytes.
- Establishes a foundational reference for future advancements in SPME technique development and application.