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Tree nut allergy.

Suzanne S Teuber1, Sarah S Comstock, Shridhar K Sathe

  • 1Division of Rheumatology, Allergy and Clinical Immunology, University of California, Davis, School of Medicine, One Shields Avenue, TB192, Davis, CA 95616, USA. ssteuber@ucdavis.edu

Current Allergy and Asthma Reports
|January 25, 2003
PubMed
Summary
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Tree nut allergy can cause severe reactions, sometimes life-threatening, even without pollen allergy. Patients with tree nut allergies should avoid other tree nuts unless clinically tested for tolerance, and always carry epinephrine.

Area of Science:

  • Allergy and Immunology
  • Clinical Medicine
  • Food Science

Background:

  • Tree nuts are linked to severe allergic reactions, including anaphylaxis.
  • Reactions can be independent of pollen allergy or involve oral allergy syndrome.
  • Co-sensitization to peanut is common in severe tree nut allergy.

Purpose of the Study:

  • To review clinical associations of tree nut allergy.
  • To discuss cross-reactivity among tree nuts.
  • To highlight management challenges in severe food allergies.

Main Methods:

  • Review of clinical studies and reports on tree nut allergy.
  • Analysis of immunoglobulin E-mediated reactions.
  • Discussion of diagnostic and management strategies.

Related Experiment Videos

Main Results:

  • Tree nut allergy can cause severe systemic reactions or oral symptoms.
  • Cross-reactivity between tree nuts necessitates caution and potential avoidance.
  • Physicians often fail to prescribe epinephrine for patients at risk of anaphylaxis.

Conclusions:

  • Avoidance of other tree nuts is recommended after diagnosis of sensitivity, pending specific challenge testing.
  • Careful management of cross-contamination is crucial.
  • Improved physician adherence to prescribing self-injectable epinephrine is vital for patient safety.