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Sphingosine 1-phosphate: a Ca2+ release mediator in the balance

K W Young1, S R Nahorski

  • 1Department of Cell Physiology and Pharmacology, Medical Sciences Building, University of Leicester, LE1 9HN, Leicester, UK. kwyl@le.ac.uk

Cell Calcium
|January 25, 2003
PubMed
Summary

Sphingosine 1-phosphate (S1P), a lipid messenger, mobilizes calcium (Ca2+). Its generation mechanism and endoplasmic reticulum actions are unclear, leaving its role as an intracellular Ca2+ release mediator uncertain.

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