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[Microfilters and blood transfusion].

H J Krebs

    Infusionstherapie Und Klinische Ernahrung
    |February 1, 1976
    PubMed
    Summary

    Microfilters effectively remove amorphous debris from fresh and stored bank blood transfusions. Stored blood showed minimal platelet aggregates and debris in smaller mesh filters, unlike standard filters.

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    Scandinavian journal of immunology·1983

    Area of Science:

    • Hematology
    • Biomedical Engineering
    • Transfusion Medicine

    Context:

    • Blood banking practices involve storing blood products for varying durations.
    • Transfusion-related microparticle accumulation is a concern.
    • Microfilters are used to improve the safety of blood transfusions.

    Purpose:

    • To evaluate the efficacy of microfilters in removing amorphous debris and platelet aggregates from fresh and stored bank blood.
    • To compare the performance of microfilters with standard 300 mu filters.

    Summary:

    • Fresh blood transfusions showed no amorphous debris after microfiltration.
    • Blood stored for 10 and 18 days yielded minimal platelet aggregates and amorphous debris in the smallest mesh microfilters.
    • Standard 300 mu filters allowed amorphous debris passage, potentially due to handling.

    Impact:

    • Microfiltration may enhance the safety of blood transfusions by reducing particulate load.
    • Further investigation into blood handling procedures is warranted to minimize debris formation.
    • Optimized microfiltration could reduce transfusion complications.

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