Related Experiment Video

Updated: Aug 13, 2026

Predicting the Effectiveness of Population Replacement Strategy Using Mathematical Modeling
20:36

Predicting the Effectiveness of Population Replacement Strategy Using Mathematical Modeling

Published on: July 4, 2007

Some aspects of a stochastic two locus selfing genetic model with selection and computer simulation

R L Welch, S C Smeach, C P Tsokos

    International Journal of Bio-Medical Computing
    |January 1, 1976
    PubMed
    Summary

    This study analyzes a two-locus selfing genetic model using Markov processes. It quantifies the impact of selection and crossover on heterozygosity over generations, introducing new calculations for expected generations and their variance.

    More Related Videos

    The Modular Design and Production of an Intelligent Robot Based on a Closed-Loop Control Strategy11:53

    The Modular Design and Production of an Intelligent Robot Based on a Closed-Loop Control Strategy

    Published on: October 14, 2017

    Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR06:18

    Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR

    Published on: July 11, 2025

    Related Concept Videos

    Types of Selection01:46

    Types of Selection

    Natural selection influences the frequencies of particular alleles and phenotypes within populations in several different ways. Primarily, natural selection can be directional, stabilizing, or disruptive. Directional selection favors one extreme trait and shifts the population towards that phenotype while selecting against individuals displaying alternate traits. Stabilizing selection favors an intermediate trait with a narrow range of variation. Deviation from the optimal phenotype towards an...
    Frequency-dependent Selection01:21

    Frequency-dependent Selection

    When the fitness of a trait is influenced by how common it is (i.e., its frequency) relative to different traits within a population, this is referred to as frequency-dependent selection. Frequency-dependent selection may occur between species or within a single species. This type of selection can either be positive—with more common phenotypes having higher fitness—or negative, with rarer phenotypes conferring increased fitness.Positive Frequency-Dependent SelectionIn positive...
    Hardy-Weinberg Principle01:49

    Hardy-Weinberg Principle

    Diploid organisms have two alleles of each gene, one from each parent, in their somatic cells. Therefore, each individual contributes two alleles to the gene pool of the population. The gene pool of a population is the sum of every allele of all genes within that population and has some degree of variation. Genetic variation is typically expressed as a relative frequency, which is the percentage of the total population that has a given allele, genotype or phenotype.In the early 20th century,...
    Mutation, Gene Flow, and Genetic Drift01:09

    Mutation, Gene Flow, and Genetic Drift

    In a population that is not at Hardy-Weinberg equilibrium, the frequency of alleles changes over time. Therefore, any deviations from the five conditions of Hardy-Weinberg equilibrium can alter the genetic variation of a given population. Conditions that change the genetic variability of a population include mutations, natural selection, non-random mating, gene flow, and genetic drift (small population size).Mechanisms of Genetic VariationThe original sources of genetic variation are mutations,...
    Genetics of Speciation02:16

    Genetics of Speciation

    Speciation is the evolutionary process resulting in the formation of new, distinct species—groups of reproductively isolated populations.The genetics of speciation involves the different traits or isolating mechanisms preventing gene exchange, leading to reproductive isolation. Reproductive isolation can be due to reproductive barriers that have effects either before or after the formation of a zygote. Pre-zygotic mechanisms prevent fertilization from occurring, and post-zygotic mechanisms...
    Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving01:29

    Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving

    Mechanistic models play a crucial role in algorithms for numerical problem-solving, particularly in nonlinear mixed effects modeling (NMEM). These models aim to minimize specific objective functions by evaluating various parameter estimates, leading to the development of systematic algorithms. In some cases, linearization techniques approximate the model using linear equations.
    In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...