[Analysis of chiral compounds by micelle electrokinetic capillary chromatography]

An overview on applications of micelle electrokinetic capillary chromatography (MECC) in chiral compounds analysis is presented. Ionic chiral surfactants such as bile salts, long-alkyl-chain surfactants and high-molecular-weight surfactants, which can migrate with electroosmosis and its electrophoretic mobility, and interact with the solutes, are employed as chiral selectors. Addition of electrically neutral chiral selectors such as cyclodextrins is also successful in MECC separation. Theory of MECC enantiomer separation is briefly described.