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Updated: Sep 27, 2026

RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
Published on: March 11, 2014
[Human papillomavirus and the risk of anogenital cancer]
Mads Melbye1, Edith Ingerslev Svare, Susanne Krüger Kjaer
1Afdeling for Epidemiologisk Forskning, Center for Epidemiologisk Grundforskning, Statens Serum Institut, Artillerivej 5, DK-2300 København S. mme@ssi.dk
Abstract:
Strong evidence suggests that virtually all cases of cervical cancer are caused by infection with oncognenic types of human papillomavirus (HPV). HPV is also found frequently in neighbouring anogenital epithelia and their neoplastic lesions. This review describes the general aspects of the natural history of anogenital HPV infections and summarises the evidence for an association between HPV and cancers of the uterine cervix, vulva, anus and penis.
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