[Application of constrained simulated annealing to 3D stereotactic radiotherapy treatment planning]

In this paper, linear programming and constrained simulated annealing are combined to optimize X-knife stereotactic radiotherapy treatment planning. In the first phase, linear programming reduces the resolution space, which is favourable to the adoption of little granularity in the second phase. Our experiment demonstrates that after the two-phase optimization, we attain the expected result.