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[Lectin activity of antitumor substances synthesized by Bacillus subtilis B-7025]
V S Podgorskiĭ1, E A Kovalenko, E I Get'man
1Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, 154 Zabolotny St., Kyiv, 03143, Ukraine.
Mikrobiolohichnyi Zhurnal (Kiev, Ukraine : 1993)
|February 1, 2003
Abstract:
Nutrient medium, which is optimal for synthesis of biologically active substances and allows obtaining stable outflow of Bacillus subtilis B-7025 to the culture medium, has been selected under the conditions of the bacillus periodic cultivation. It has been established that these substances are extracellular lectins with high activity and carbohydrate specificity to fructose-1.6-di phosphate, N-acetylneuraminic acid and glucose derivatives: D-glucuronic acid and D-glucosamine.