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[Eosinophilic proctocolitis induced by foods. Report of a case]
Miguel Angel Cordero Miranda1, Virginia Blandón Vijil, Norma Isabel Reyes Ruiz
1Departamento de alergia e inmunología clinica, Hospital Infantil de México Federico Gómez.
Insights
Food-induced eosinophilic proctocolitis causes bloody stools in infants. Dietary protein elimination using hydrolyzed formula rapidly resolved symptoms in an early infant case.
Area of Science:
- Pediatric Gastroenterology
- Allergy and Immunology
Background:
- Food-induced eosinophilic proctocolitis is a significant cause of hematochezia in early infancy.
- Clinical presentation and laboratory findings are often nonspecific, delaying diagnosis.
Observation:
- A case of an infant presenting with fresh blood in stools at 50 days of life is detailed.
- Colonoscopy and biopsy revealed significant eosinophil infiltration and lymphoid nodular hyperplasia.
Findings:
- Histopathological examination confirmed eosinophilic proctocolitis with high eosinophil counts (40-50 per HPF).
- Elimination of dietary offending proteins via an extensively hydrolyzed casein-based formula and soy led to rapid clinical resolution.
Implications:
- Early diagnosis and dietary management are crucial for treating food-induced eosinophilic proctocolitis.
- Extensively hydrolyzed formulas are effective in managing this condition, preventing complications.
Abstract:
The food-induced eosinophilic proctocolitis is a major cause of blood-tinged stools and appears in the first two months of life. The infant is generally described as well, but the clinical features and laboratory results are often nonspecific. We present an early infant with fresh blood stools at 50 days. The colonoscopy and biopsy of the rectum and lower sigmoid revealed lymphoid nodular hyperplasia of the submucose and eosinophil infiltration (40 to 50 per high power field) of the lamina propria and intraepithelial. Elimination of the offending protein from the diet, through the use of an extensively hydrolyzed casein-based formula and soy, lead to clinical resolution of bleeding at 48 hours. We made a review of the case.