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Adrenergic contribution during acclimatization to high altitude: perspectives from Pikes Peak
Robert S Mazzeo1, John T Reeves
1Department of Kinesiology and Applied Physiology, University of Colorado, Boulder 80309, USA. mazzeo@colorado.edu
Exercise and Sport Sciences Reviews
|February 4, 2003
Abstract:
We have examined the sympathoadrenal responses to both acute and chronic high-altitude exposure at the summit of Pikes Peak, CO, in both men and women. A dissociation between the adrenal medullary response (acute) with that of the sympathetic nervous system (chronic) is observed. Both alpha- and beta-adrenergic contributions to key metabolic and physiologic adjustments to high-altitude exposure are evident.