Related Experiment Videos
Optic neuritis: evaluation with orbital Doppler sonography
Kamil Karaali1, Utku Senol, Hülya Aydin
1Department of Radiology, Akdeniz University School of Medicine, 07070 Antalya, Turkey. karaali@med.akdeniz.edu.tr
Radiology
|February 4, 2003
Summary
Doppler sonography revealed increased orbital blood flow velocities in patients with acute optic neuritis. Specifically, peak systolic and end diastolic velocities in the ophthalmic artery were significantly elevated in affected eyes.
Area of Science:
- Ophthalmology
- Neuro-ophthalmology
- Medical Imaging
Background:
- Optic neuritis is an inflammatory condition affecting the optic nerve.
- Assessing orbital hemodynamics may provide insights into the pathophysiology of optic neuritis.
Purpose of the Study:
- To evaluate orbital blood flow velocities using Doppler sonography in patients diagnosed with acute unilateral optic neuritis.
Main Methods:
- Doppler sonography was performed on 20 patients with acute unilateral optic neuritis.
- Measurements included peak systolic velocity (PSV), end diastolic velocity (EDV), and resistive index (RI) in the ophthalmic and central retinal arteries.
- Affected and unaffected orbits were compared using a paired t test.
Main Results:
- Ophthalmic artery PSV and EDV were significantly increased in affected orbits (P <.001 and P <.05, respectively).
- Resistive indexes in the ophthalmic arteries showed no significant difference between affected and unaffected orbits (P >.05).
- No statistically significant differences were observed in PSV, EDV, or RI in the central retinal arteries.
Conclusions:
- Acute optic neuritis is associated with increased ophthalmic artery blood flow velocities.
- Doppler sonography can detect hemodynamic changes in the ophthalmic artery in acute optic neuritis.