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[Establishment of a rabbit model of Acanthamoeba keratitis]
Abstract
Aim:
To establish an animal model of Acanthamoeba keratitis.
Methods:
Six New Zealand white rabbits were each injected intrastromally with Acanthamoeba suspension 3 days after subconjunctival injection with dexamethasone.
Results:
All of the 6 rabbits developed keratitis. Acanthamoeba protozoa were identified by the methods of corneal scraping with 10% potassium hydroxide wet mount examined under microscope, corneal protozoa culture and pathological section examination.
Conclusion:
A rabbit model of Acanthamoeba keratitis was established.