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Ocular blood flow in healthy and primary open-angle glaucomatous eyes
Hakki Birinci1, Murat Danaci, Ihsan Oge
1Department of Ophthalmology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey. habirinci@yahoo.com
Purpose:
To evaluate blood flow parameters in the ophthalmic artery, in the posterior ciliary arteries and in the central retinal artery in eyes with primary open-angle glaucoma.
Methods:
Hemodynamic parameters were evaluated by color Doppler imaging in 48 patients with primary open-angle glaucoma and 42 age-matched normal control subjects. Peak systolic velocity (Pv), end-diastolic velocity (Ev), and resistive index (RI) were calculated in the central retinal artery, short posterior ciliary arteries and the ophthalmic artery.
Results:
The analysis of the ocular blood flow velocities in the central retinal artery, short posterior ciliary arteries and the ophthalmic artery revealed a significant reduction in peak systolic velocity and end-diastolic velocity with an increase in resistive index in primary open-angle glaucoma compared with controls (p < 0.05).
Conclusion:
Our data indicate primary open-angle glaucoma to be associated with a decreased flow velocity and increased resistive index in the ocular vasculature.