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Updated: Jul 31, 2026

Procedure for Adaptive Laboratory Evolution of Microorganisms Using a Chemostat
Published on: September 20, 2016
Minimal model for genome evolution and growth
Li-Ching Hsieh1, Liaofu Luo, Fengmin Ji
1Department of Physics, National Central University, Chungli, Taiwan 320.
Abstract:
Textual analysis of typical microbial genomes reveals that they have the statistical characteristics of a DNA sequence of a much shorter length. This peculiar property supports an evolutionary model in which a genome evolves by random mutation but primarily grows by random segmental duplication. That genomes grew mostly by duplication is consistent with the observation that repeat sequences in all genomes are widespread and intragenomic and intergenomic homologous genes are preponderant across all life forms.
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