Automation of biomolecular NMR screening

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Updated: Sep 27, 2026

NMR-Based Fragment Screening in a Minimum Sample but Maximum Automation Mode
09:19

NMR-Based Fragment Screening in a Minimum Sample but Maximum Automation Mode

Published on: June 4, 2021

Alfred Ross1, Hans Senn

  • 1Hoffmann LaRoche AG, Department for Biostructural Research (PRBT), Grenzacher Str., CH-4070 Basel, Switzerland. alfred.ross@roche.com

Current Topics in Medicinal Chemistry
|February 7, 2003
PubMed

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Applications Of NMR In Biology01:25

Applications Of NMR In Biology

Nuclear magnetic resonance (NMR) spectroscopy is a very valuable analytical technique for researchers. It has been used for more than 50 years as an analytical tool. F. Bloch and E. Purcell formulated NMR in 1946 and won the 1952 Nobel Prize in Physics  for their work. Biological macromolecules such as proteins, nucleic acids, lipids, and organic molecules including pharmaceutical compounds, can be studied using this versatile tool that exploits the magnetic properties of certain nuclei.
The...