Related Experiment Videos
Automation of biomolecular NMR screening
1Hoffmann LaRoche AG, Department for Biostructural Research (PRBT), Grenzacher Str., CH-4070 Basel, Switzerland. alfred.ross@roche.com
Current Topics in Medicinal Chemistry
|February 7, 2003
Abstract:
For NMR based screening we review equipment needed for automated preparation of samples and acquisition of a large number of data sets. Hardware connecting lab-bench and NMR spectrometer is described. We focus on software used for automated calculation of the similarity between spectra - a prerequisite for the identification of test compounds interacting with a target-molecule.