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[Herbal preparations have both effects and side effects. Widespread usage dictates knowledge among physicians].

Karin Mattsson1, Inger Nilsson

  • 1karin.mattsson@apoteket.se

Lakartidningen
|February 8, 2003
PubMed
Summary

This review examines the efficacy and safety of popular herbal supplements like Ginkgo biloba and St. John's wort. While some show clinical benefits, all have potential adverse effects, and more research is needed.

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Area of Science:

  • Pharmacology and pharmacognosy of herbal medicinal products.
  • Clinical trial methodology and evidence-based medicine.
  • Regulatory affairs concerning herbal supplements.

Context:

  • Overview of commonly used herbal supplements including Ginkgo biloba, St. John's wort, ginseng, Echinacea, saw palmetto, and kava.
  • Focus on clinical data and experiences from the United States.
  • Highlights the regulatory differences between American and Swedish herbal medicine legislation.

Purpose:

  • To provide a clinically oriented overview of the efficacy and safety of selected herbal medicinal products.
  • To evaluate the existing clinical data supporting the use of these herbs.
  • To identify potential adverse effects associated with their use.

Summary:

  • Clinical evidence supports the efficacy of some herbal drugs, but none are entirely free from adverse effects.

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  • Existing clinical trials for many herbal products are often limited in size, duration, and scope.
  • The lack of long-term studies is a significant limitation, given the chronic use of many of these supplements.

    • Impact:

    • Informs healthcare professionals and consumers about the current evidence base for popular herbal remedies.
    • Underscores the need for more rigorous and extensive research into the safety and efficacy of herbal medicines.
    • Provides context on regulatory landscapes affecting herbal product availability and use.