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[Correlation between blood pressure variability and left ventricular hypertrophy in patients with primary
Yang Cao1, Shui-ping Zhao, Lin Luo
1Cardiovascular Laboratory, Second Xiangya Hospital, Central South University, Changsha 410011, China.
Objective:
To study the correlation between blood pressure variability (BPV) and left ventricular hypertrophy (LVH) in patients with primary hypertension.
Methods:
We monitored the 24-hour ambulatory blood pressure and determined the left ventricular mass index (LVMI) by two dimensional echocardiography in 87 patients with primary hypertension (PH) and 26 normal controls.
Results:
The LVMI in the PH patients was significantly higher than that in the controls. It was positively correlated to the average level of the 24-hour systolic blood pressure (24 h-SBP), nighttime systolic blood pressure (n-SBP), and nighttime diastolic blood pressure (n-DBP) (r = 0.183, P < 0.05; r = 0.275, P < 0.01; r = 0.243, P < 0.05, respectively). It was also negatively correlated to the 24-hour systolic blood pressure variability (24 h-SBPV) and the daytime systolic blood pressure variability (d-SBPV) (r = -0.253, P < 0.01; r = -0.186, P < 0.05, respectively). The 24 h-SBPV in the patients with LVH was significantly lower than that of those without LVH, but there was no significant difference in d-SBPV and n-SBPV between the PH patients with LVH and those without LVH.
Conclusion:
The 24 h-SBPV is valuable in predicting LVH in hypertension.