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Updated: Sep 27, 2026

Assessing the Putative Anticryptococcal Properties of Crude and Clarified Extracts from Mollusks
Published on: December 2, 2022
[Chemical constituents from marine fungus Penicillium thomii]
Ting Jiang1, Li Tian, Ai-hua Guo
1National Research Laboratories of Natural and Biomimetic Drugs, Peking University, Beijing 100083, China.
Aim:
To investigate the bioactive constituents from the mycelium of Penicillium thomii. Which isolated from Anemone collected in Qingdao beach.
Methods:
The constituents were separated by using various chromatography and the structures were identified on the basis of extensive spectral analysis.
Results:
Five compounds, namely penicillixanthone A (I), p-methylbenzolic acid (II), 1-O-hexadecanoyl-2-O-(9-octadecenoyl)-3-O-(9, 12-octadecadienoyl) glycerol (III), 5 alpha, 8 alpha-epidioxy-24 zeta-methylcholesta-6, 22-dien-3 beta-ol (IV) and 1, 6, 8-trihydroxyl-3-methyl-9, 10-anthracenedione (V), were isolated from the mycelium of Penicillium thomii.
Conclusion:
Penicillixanthone A is a new compound, while the others are isolated from Penicillium thomii for the first time.
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