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Radiopaque nano and polymeric materials for atherosclerosis imaging, embolization and other catheterization

Li Tian1, Linfeng Lu1, James Feng2

  • 1Department of Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

Acta Pharmaceutica Sinica. B
|June 9, 2018
PubMed

Insights

This review covers radiopaque materials for imaging and treating atherosclerosis, a major cause of cardiovascular disease (CVD). It highlights advancements in radiopaque agents and devices used in catheterization procedures for CVD diagnosis and treatment.

Area of Science:

  • Biomaterials Science
  • Medical Imaging
  • Cardiovascular Medicine

Background:

  • Cardiovascular diseases (CVDs) are a leading cause of death, with atherosclerosis being a major contributor.
  • Effective imaging and interventional tools are crucial for managing CVDs.

Purpose of the Study:

  • To review radiopaque nano and polymeric materials for atherosclerosis imaging and catheterization procedures.
  • To discuss recent progress in radiopaque imaging agents and devices for CVD diagnosis and treatment.

Main Methods:

  • Review of the physics of radiopacity and X-ray/CT.
  • Discussion of clinically used contrast agents.
  • Analysis of recent developments in radiopaque materials for medical applications.

Main Results:

  • Exploration of radiopaque imaging agents for atherosclerosis.
  • Overview of radiopaque embolic agents, drug-eluting beads, and medical devices for catheterization.
  • Presentation of strategies for introducing radiopacity in polymers and their applications.

Conclusions:

  • Radiopaque materials play a vital role in advancing the diagnosis and treatment of cardiovascular diseases.
  • Ongoing research in radiopaque polymers and agents offers promising solutions for atherosclerosis management and catheterization procedures.

Keywords:
AtherosclerosisCTEmbolizationInferior vena cava filtersPlaqueRadiopaque contrast nanoparticles and materialsStenosisVascular diseasesX-ray

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