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[Studies on chemical constituents of Uvaria macrophylia]
Hai-ling Zhang1, Si Wang, Ruo-yun Chen
1Institute of Materia Medica, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100050, China.
Aim:
To study the chemical constituents from Uvaria macrophylla Roxb. (Annonaceae).
Methods:
Various chromatography techniques were used to separate and purify the constituents. Their structures were elucidated by UV, IR, MS, 1HNMR, 13CNMR, 1H-1H COSY, HMQC and HMBC spectral analysis.
Results:
Seven compounds have been isolated from the CHCl3 extract of the roots of the U. macrophylla. They were identified as macrophyllin (1), onysilin (2), taraxerol (3), 3,5-dimethoxy benzyl benzoic acid ester (4), benzoic acid (5), beta-sitosterol (6) and daucosterol (7).
Conclusion:
Compound 1 is a new compound. Compounds 2-7 were obtained from this plant for the first time.
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