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Updated: Mar 19, 2026

Author Spotlight: Discovering New Alkaloids in Plants with Advanced Mass Spectrometry Techniques
Published on: March 8, 2024
Protostane triterpenes from the rhizome of Alisma plantago-aquatica
Gu Zhao1, Wan-Qi Zhang1, Jing-Han Zhang1
1State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Abstract:
A new protostane triterpene named 11-deoxy-25-O-ethylalisol A (1), together with four known analogues (2-5), were isolated from the dried rhizome of Alisma plantago-aquatica. The structure of the new compound was established by chemical methods and spectroscopic analysis, and the single crystal X-ray diffraction analyses were conducted on the compounds 2-5. Additionally, compounds 1-5 were tested for their cytotoxicity against six human tumor cell lines, hepatoprotective and anti-inflammatory activities.
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