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Related Experiment Videos

Deodorants: an experimental provocation study with cinnamic aldehyde.

Magnus Bruze1, J D Johansen, K E Andersen

  • 1Department of Occupational and Environmental Dermatology, University Hospital, Malmö, Sweden. magnus.bruze@derm.mas.lu.se

Journal of the American Academy of Dermatology
|February 13, 2003
PubMed
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Deodorants with cinnamic aldehyde can cause axillary dermatitis in allergic individuals. This study confirms cinnamic aldehyde in deodorants triggers skin reactions in sensitive patients.

Area of Science:

  • Dermatology
  • Allergology
  • Cosmetic Science

Background:

  • Axillary dermatitis is frequently linked to fragrance contact allergy.
  • Individuals often suspect deodorants as the cause of their dermatitis.

Purpose of the Study:

  • To assess the role of cinnamic aldehyde in deodorants for developing axillary dermatitis.
  • To evaluate this in individuals with and without cinnamic aldehyde allergy.

Main Methods:

  • Patch testing with deodorants and cinnamic aldehyde solutions.
  • Repeated open application tests with deodorants containing varying cinnamic aldehyde concentrations.

Main Results:

  • Positive reactions occurred exclusively in patients allergic to cinnamic aldehyde.

Related Experiment Videos

  • Reactions were localized to the axilla where cinnamic aldehyde-containing deodorants were applied.

    • Conclusions:

    • Deodorants with 0.01% to 0.32% cinnamic aldehyde can induce axillary dermatitis.
    • Twice-daily application on healthy skin may lead to dermatitis within weeks.