Related Experiment Videos
[Effect of sinamine on withdrawal symptom and neurotransmitter of morphine-dependent rats]
Caiyun Wang1, Zhixian Mo, Qiushuang Zhu
1First Military Medical University, Guangzhou 510515.
Zhong Yao Cai = Zhongyaocai = Journal of Chinese Medicinal Materials
|February 14, 2003
Abstract
Objective:
To study on the detoxification effect of sinamine in morphine-dependent rats.
Methods:
Morphine-dependent rats were induced by injecting morphine on dosage increasing by degrees, then treated with medication. The withdrawal symptoms, body weight and NE, DA, 5-HT in the brain were tested.
Results:
Sinamine could alleviate withdrawal symptom, reablement body weight, inhibit neurotransmitter in the brain.
Conclusion:
Sinamine have effects on morphine-dependent rats which may relate to modulating neurotransmitter.