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Correlation between structure, aggregation behaviour and cellular toxicity of anti-HIV catanionic analogues of
Muriel Blanzat1, Emile Perez, Isabelle Rico-Lattes
1Laboratoire des Interactions Moléculaire et Réactivité Chimique et Photochimique, CNRS UMR 5623, Université P. Sabatier, 118 route de Narbonne, 31062 Toulouse cedex, France. blanzat@chimie.ups-tlse.fr
Abstract:
The self-association process of catanionic analogues of galactosylceramide and in particular the arrangement of their hydrophobic part seems to play a key role in their cellular toxicity